Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Cl- | activates | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | mutants K361,365 and mutant K961,963, in which one active site has been inactivated by site-directed mutagenesis. Both active centers are catalytically active in the cell membrane-anchored enzyme and convert angiotensin I to angiotensin II | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km values for wild-type and mutant enzymes | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | contains zinc | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
wild-type enzyme and mutants in which one active site has been inactivated by site-directed mutagenesis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hippuryl-Phe-Arg + H2O | - |
Homo sapiens | hippuric acid + Phe-Arg | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km values for wild-type and mutant enzymes | Homo sapiens |